Seeded
PAOK FC,
R. Standard de Liège,
PSV Eindhoven,
Sporting Clube de Portugal,
Beşiktaş JK,
Athletic Club,
FC Metalist Kharkiv,
Club Brugge KV,
Club Atlético de Madrid,
FC Schalke 04,
FC Twente,
RSC Anderlecht,
Manchester City FC*,
Manchester United FC*,
Valencia CF*,
Olympiacos CF*
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Unseeded
FC Rubin Kazan,
Hannover 96,
Legia Warszawa,
S.S. Lazio,
Stoke City FC,
FC Salzburg,
AZ Alkmaar,
SC Braga,
Udinese Calcio,
FC Steaua Bucureşti,
Wisła Kraków,
FC Lokomotiv Moskva,
Trabzonspor AŞ*,
AFC Ajax*,
FC Porto*,
FC Viktoria Plzeň*
